HIGH CARBON MONOXIDE SYMPTOMS VERIFICATION

This led to elevated carbon monoxide and carboxyhaemoglobin levels in the patient’s body.

The destroyed red blood cells also released haemoglobin that was broken down by the enzyme haem oxygenase. WAIHA, with its devastating destruction of red blood cells, meant there was not enough oxygen to meet bodily demands. While symptoms can occur gradually over several weeks, rapid onset within days has been noted in some cases. 3 The most common type – the one our patient was diagnosed with – is warm autoantibody autoimmune haemolytic anaemia (WAIHA), which is when the antibodies targeting red blood cells react optimally at the body’s average core temperature of 37☌. This disease affects between just one and three patients per 100,000 every year. 2 However, when destruction is not triggered per usual but by antibodies produced because one’s immune system has identified the body’s red blood cells as unwanted substances, the result is autoimmune haemolytic anaemia. After an average lifecycle of 120 days, battle-worn red blood cells are cleared by macrophage cells programmed to detect, consume and destroy cells at the end of their life.

Her red blood cells were being destroyed – something that happens normally.

HIGH CARBON MONOXIDE SYMPTOMS VERIFICATION

Thirty minutes prior to the time-of-death call, when hospital staff were attempting resuscitation, verification came through that the woman had a rare type of haemolytic anaemia. The deceased woman’s own body had poisoned her. Turns out, environmental carbon monoxide poisoning was a red herring. It was alleged he engineered his wife’s exposure to carbon monoxide, with evaluation of duct showing car exhaust exposure and the prosecution introducing images of ‘soot marks above the vent in her room’ in court. Forward in time and back in North Carolina, there was no evidence of evil engineering by anyone. At least, not one investigators had seen before.Īpproximately 500 miles away and roughly 15 years earlier, an apparent accidental carbon monoxide poisoning of another woman was initially blamed on a faulty gas water heater. Within five years, blame had shifted to the women’s husband and he was convicted of murder. Throughout the home, the fire captain was getting carbon monoxide readings of zero parts per million, and all potential carbon monoxide sources at the location were ruled out. This was not carbon monoxide poisoning. Law enforcement also assisted at the scene, with a detective determining that it was not a carbon monoxide detector that had been triggered during the paramedics’ visit. Over 400 people die in the US from accidental carbon monoxide poisoning each year, where it is the leading cause of non-drug poisoning, with non-fire-associated environmental exposures being the main accidental culprit.Īn OCME investigator worked with the fire marshal to inspect the deceased woman’s home for the carbon monoxide source. Her case was handed over to the North Carolina Office of the Chief Medical Examiner (OCME) to identify the lethal sequence of events that led to this apparent carbon monoxide poisoning. But 19 hours after paramedics first reached her, she was pronounced dead. For about an hour, medical professionals attempted resuscitation.

All further attempts to render aid brought no improvement and she went into cardiac arrest. Then, instead of continued positive progress, she took a turn for the worse. With emergency treatment, she seemed to improve and become more responsive. Initial blood work at the emergency department indicated the patient did not have enough functioning red blood cells or haemoglobin.

CO was displacing O 2, tying up haemoglobin and keeping this transport protein in red blood cells from its main job – getting oxygen to tissues. It was 25% – far above a normal value of approximately 2%. En route to the hospital, paramedics used a pulse CO-oximeter to determine their patient’s carboxyhaemoglobin level. Paramedics, suspecting environmental carbon monoxide poisoning and concerned over the indoor air quality, moved their patient outside where she ‘appeared less disoriented’. High carbon monoxide levels can cause disorientation, unconsciousness, coma, cardiorespiratory failure and death. Dizziness, headache, nausea and vomiting are all low-level carbon monoxide exposure symptoms. It was that last type that seemed to correspond to her symptoms. She could not recall what type of alarm it was – burglar, smoke or carbon monoxide. While paramedics were rendering aid, an alarm rang out inside the woman’s home. 1 Responding paramedics noted additional issues – lack of focus and factual recall, as well as drowsiness. After two days of nausea, dizziness and fatigue, a 60-year old woman in North Carolina, US, called the emergency services to her home.

High carbon monoxide symptoms